Issue 27, 2016
From the journal:

Nanoscale

Localized committed differentiation of neural stem cells based on the topographical regulation effects of TiO2 nanostructured ceramics†

Xiaoning Mou,‡a   Shu Wang,‡ab   Weibo Guo,ab   Shaozheng Ji,c   Jichuan Qiu,c   Deshuai Li,ab   Xiaodi Zhang,ab   Jin Zhou,d   Wei Tang,e   Changyong Wang*d  and  Hong Liu*ac  

* Corresponding authors

a Beijing Institute of Nanoenergy and Nanosystems, Chinese Academy of Sciences; National Center for Nanoscience and Technology (NCNST), Beijing, P. R. China
E-mail: hongliu@sdu.edu.cn

b University of Chinese Academy of Sciences, Beijing, China

c State Key Lab of Crystal Materials, Shandong University, 27 Shandanan Road, Jinan, China

d Department of Advanced Interdisciplinary Studies, Institute of Basic Medical Sciences and Tissue Engineering Research Center, Academy of Military Medical Sciences, Beijing 100850, China

e Department of Pathogenic Biology, School of Medicine, Shandong University, Jinan, China

Abstract

In this study, a porous-flat TiO2 micropattern was fabricated with flat and nanoporous TiO2 ceramics for investigating the effect of topography on neural stem cell (NSC) differentiation. This finding demonstrates that localized committed differentiation could be achieved in one system by integrating materials with different topographies.

Graphical abstract: Localized committed differentiation of neural stem cells based on the topographical regulation effects of TiO2 nanostructured ceramics

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Article information

DOI
https://doi.org/10.1039/C6NR01874B
Article type
Communication
Submitted
04 Mar 2016
Accepted
13 Jun 2016
First published
14 Jun 2016

Nanoscale, 2016,8, 13186-13191

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Localized committed differentiation of neural stem cells based on the topographical regulation effects of TiO2 nanostructured ceramics

X. Mou, S. Wang, W. Guo, S. Ji, J. Qiu, D. Li, X. Zhang, J. Zhou, W. Tang, C. Wang and H. Liu, Nanoscale, 2016, 8, 13186 DOI: 10.1039/C6NR01874B

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