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Issue 9, 2016
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Hydrophilic GO/Fe3O4/Au/PEG nanocomposites for highly selective enrichment of glycopeptides

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Abstract

GO/Fe3O4/Au/PEG nanocomposites were synthesized via bonding gold nanoparticles on magnetic graphene oxide using polyethylenimine as the reducing and immobilizing reagent, followed by thiol-terminal polyethylene glycol immobilization. With the use of this nanocomposite, 255 glycopeptides, mapped to 127 different glycoproteins, were identified from human serum, demonstrating its great potential for glycosylation analysis.

Graphical abstract: Hydrophilic GO/Fe3O4/Au/PEG nanocomposites for highly selective enrichment of glycopeptides

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Publication details

The article was received on 17 Nov 2015, accepted on 02 Feb 2016 and first published on 02 Feb 2016


Article type: Communication
DOI: 10.1039/C5NR08126B
Citation: Nanoscale, 2016,8, 4894-4897

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    Hydrophilic GO/Fe3O4/Au/PEG nanocomposites for highly selective enrichment of glycopeptides

    B. Jiang, Q. Wu, N. Deng, Y. Chen, L. Zhang, Z. Liang and Y. Zhang, Nanoscale, 2016, 8, 4894
    DOI: 10.1039/C5NR08126B

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