Extremely low frequency alternating magnetic field–triggered and MRI–traced drug delivery by optimized magnetic zeolitic imidazolate framework-90 nanoparticles

Abstract

An extremely low frequency alternating magnetic field (ELF-AMF) was demonstrated to be able to effectively trigger drug release from carefully engineered magnetic ZIF-90 nanoparticles. The embedded Fe₃O₄ nanoparticles or alternatively Gd₂O₃ nanoparticles serve as effective MRI tracers for potential visualization of drug delivery to ensure drug delivery accuracy.