Issue 42, 2015
From the journal:

Nanoscale

Compact chelator-free Ni-integrated CuS nanoparticles with tunable near-infrared absorption and enhanced relaxivity for in vivo dual-modal photoacoustic/MR imaging†

Duyang Gao,‡ac   Pengfei Zhang,‡ad   Chengbo Liu,‡b   Chi Chen,a   Guanhui Gao,a   Yayun Wu,a   Zonghai Sheng,a   Liang Songb  and  Lintao Cai*a  

* Corresponding authors

a Guangdong Key Laboratory of Nanomedicine, CAS Key Laboratory for Health Informatics, Shenzhen Bioactive Materials Engineering Lab for Medicine, Institute of Biomedicine and Biotechnology, Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences, Shenzhen, P. R. China
E-mail: lt.cai@siat.ac.cn

b Research Lab for Biomedical Optics and Molecular Imaging, Shenzhen Key Lab for Molecular Imaging, Institute of Biomedical and Health Engineering, Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences, Shenzhen 518055, P. R. China

c Bioimaging Core, Faculty of Health Sciences, University of Macau, Macao, China

d Division of Biomedical Engineering, The Hong Kong University of Science and Technology, Clear Water Bay, Kowloon, China

Abstract

A chelator-free doping method is developed for constructing a Ni-integrated CuS nanostructure as a novel PA/MRI contrast agent. It exhibits tunable near-infrared absorption. Moreover, the hybrid nanostructure has demonstrated a dramatically enhanced T1 relaxivity compared with Ni ions. Due to these unique properties, chelator-free nanoparticles have been successfully applied for in vivo PA/MRI dual-modal imaging.

Graphical abstract: Compact chelator-free Ni-integrated CuS nanoparticles with tunable near-infrared absorption and enhanced relaxivity for in vivo dual-modal photoacoustic/MR imaging

About
Cited by
Related
Download options Please wait...

Supplementary files

Article information

DOI
https://doi.org/10.1039/C5NR05237H
Article type
Communication
Submitted
04 Aug 2015
Accepted
19 Sep 2015
First published
30 Sep 2015

Nanoscale, 2015,7, 17631-17636

Author version available

Download author version (PDF)

Permissions

Request permissions

Compact chelator-free Ni-integrated CuS nanoparticles with tunable near-infrared absorption and enhanced relaxivity for in vivo dual-modal photoacoustic/MR imaging

D. Gao, P. Zhang, C. Liu, C. Chen, G. Gao, Y. Wu, Z. Sheng, L. Song and L. Cai, Nanoscale, 2015, 7, 17631 DOI: 10.1039/C5NR05237H

To request permission to reproduce material from this article, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Read more about how to correctly acknowledge RSC content.

Social activity

Spotlight

Advertisements