Issue 40, 2015
From the journal:

Nanoscale

An easy-to-prepare mini-scaffold for DNA origami†

S. Brown,*a   J. Majikes,b   A. Martínez,c   T. M. Girón,c   H. Fennell,b   E. C. Samanoc  and  T. H. LaBean*b  

* Corresponding authors

a Niels Bohr Institute, University of Copenhagen, Blegdamsvej 17, Copenhagen 2100, Denmark
E-mail: stanley@nbi.ku.dk

b Department of Materials Science & Engineering, North Carolina State University, Raleigh, North Carolina 27606, USA
E-mail: thlabean@ncsu.edu

c Centro de Nanociencias y Nanotecnología, Universidad Nacional Autónoma de México, Ensenada, B.C., México

Abstract

The DNA origami strategy for assembling designed supramolecular complexes requires ssDNA as a scaffold strand. A system is described that was designed approximately one third the length of the M13 bacteriophage genome for ease of ssDNA production. Folding of the 2404-base ssDNA scaffold into a variety of origami shapes with high assembly yields is demonstrated.

Graphical abstract: An easy-to-prepare mini-scaffold for DNA origami

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Article information

DOI
https://doi.org/10.1039/C5NR04921K
Article type
Communication
Submitted
22 Jul 2015
Accepted
25 Aug 2015
First published
17 Sep 2015

Nanoscale, 2015,7, 16621-16624

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An easy-to-prepare mini-scaffold for DNA origami

S. Brown, J. Majikes, A. Martínez, T. M. Girón, H. Fennell, E. C. Samano and T. H. LaBean, Nanoscale, 2015, 7, 16621 DOI: 10.1039/C5NR04921K

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