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Issue 43, 2015
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A reversible metal ion fueled DNA three-way junction molecular device for “turn-on and -off” fluorescence detection of mercury ions (II) and biothiols respectively with high selectivity and sensitivity

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Abstract

We constructed a reversible molecular device in the nanoscale based on a DNA three-way junction (3WJ) fueled by Hg2+ binding and sequestration. It is highly responsive to external stimuli, which brings about optically detectable global structural changes. Such a DNA device can serve as a novel “turn-on and -off” fluorescent sensor for Hg2+ and biothiol detection with high selectivity and sensitivity.

Graphical abstract: A reversible metal ion fueled DNA three-way junction molecular device for “turn-on and -off” fluorescence detection of mercury ions (II) and biothiols respectively with high selectivity and sensitivity

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Publication details

The article was received on 13 Jul 2015, accepted on 24 Sep 2015 and first published on 21 Oct 2015


Article type: Communication
DOI: 10.1039/C5NR04688B
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Citation: Nanoscale, 2015,7, 18044-18048

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    A reversible metal ion fueled DNA three-way junction molecular device for “turn-on and -off” fluorescence detection of mercury ions (II) and biothiols respectively with high selectivity and sensitivity

    L. Ma, G. Wu, Y. Li, P. Qin, L. Meng, H. Liu, Y. Li and A. Diao, Nanoscale, 2015, 7, 18044
    DOI: 10.1039/C5NR04688B

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