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Issue 16, 2014
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Cancer-targeted functional gold nanoparticles for apoptosis induction and real-time imaging based on FRET

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Abstract

A versatile gold nanoparticle-based multifunctional RB-DEVD-AuNP-DTP has been developed to induce the targeted apoptosis of cancer cells and image in real time the progress of the apoptosis. The multifunctional nanoparticles were demonstrated to have the ability to initiate mitochondria-dependent apoptosis and activate caspase-3 for real-time imaging of the progression of apoptosis.

Graphical abstract: Cancer-targeted functional gold nanoparticles for apoptosis induction and real-time imaging based on FRET

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Article information


Submitted
09 May 2014
Accepted
12 Jun 2014
First published
13 Jun 2014

Nanoscale, 2014,6, 9531-9535
Article type
Communication

Cancer-targeted functional gold nanoparticles for apoptosis induction and real-time imaging based on FRET

W. Chen, G. Luo, X. Xu, H. Jia, Q. Lei, K. Han and X. Zhang, Nanoscale, 2014, 6, 9531
DOI: 10.1039/C4NR02516D

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