Issue 15, 2014

An oligonucleotide-based label-free luminescent switch-on probe for RNA detection utilizing a G-quadruplex-selective iridium(iii) complex

Abstract

We report herein the synthesis and application of a novel G-quadruplex-selective luminescent iridium(III) complex for the construction of an oligonucleotide-based, label-free, rapid and convenient luminescent RNA detection platform.

Graphical abstract: An oligonucleotide-based label-free luminescent switch-on probe for RNA detection utilizing a G-quadruplex-selective iridium(iii) complex

Supplementary files

Article information

Article type
Communication
Submitted
27 Jan 2014
Accepted
27 Mar 2014
First published
01 Apr 2014

Nanoscale, 2014,6, 8489-8494

Author version available

An oligonucleotide-based label-free luminescent switch-on probe for RNA detection utilizing a G-quadruplex-selective iridium(III) complex

D. Ma, S. Lin, K. Leung, H. Zhong, L. Liu, D. S. Chan, A. Bourdoncle, J. Mergny, H. D. Wang and C. Leung, Nanoscale, 2014, 6, 8489 DOI: 10.1039/C4NR00541D

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