Issue 17, 2013
From the journal:

Nanoscale

Replenishable dendrimer–nanoparticle hybrid membranes for sustained release of therapeutics†

Myoung-Hwan Park,‡ab   Sung Tae Kim,‡a   Subinoy Rana,a   David Solfiell,a   Youngdo Jeong,a   Bradley Duncan,a   Bo Yan,a   Büşra Aksoya  and  Vincent M. Rotello*a  

* Corresponding authors

a Department of Chemistry, University of Massachusetts, 710 North Pleasant St., Amherst, MA 01003, USA
E-mail: rotello@chem.umass.edu
Fax: +82 1 413 545 4490
Tel: +82 1 413 545 2058

b Department of Chemistry, Sahmyook University, Seoul 139-742, South Korea

Abstract

We report a versatile hybrid membrane for sustained release therapeutic delivery systems. Chemically-directed assembly of a hybrid membrane of nanoparticles and dendrimers was integrated with a fluidic delivery device and a refillable drug reservoir, providing continuous sustained release.

Graphical abstract: Replenishable dendrimer–nanoparticle hybrid membranes for sustained release of therapeutics

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Article information

DOI
https://doi.org/10.1039/C3NR02049E
Article type
Communication
Submitted
24 Apr 2013
Accepted
22 Jun 2013
First published
26 Jun 2013

Nanoscale, 2013,5, 7805-7808

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Replenishable dendrimer–nanoparticle hybrid membranes for sustained release of therapeutics

M. Park, S. T. Kim, S. Rana, D. Solfiell, Y. Jeong, B. Duncan, B. Yan, B. Aksoy and V. M. Rotello, Nanoscale, 2013, 5, 7805 DOI: 10.1039/C3NR02049E

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