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Issue 19, 2013
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Nanomedicine for treating spinal cord injury

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Abstract

Spinal cord injury results in significant mortality and morbidity, lifestyle changes, and difficult rehabilitation. Treatment of spinal cord injury is challenging because the spinal cord is both complex to treat acutely and difficult to regenerate. Nanomaterials can be used to provide effective treatments; their unique properties can facilitate drug delivery to the injury site, enact as neuroprotective agents, or provide platforms to stimulate regrowth of damaged tissues. We review recent uses of nanomaterials including nanowires, micelles, nanoparticles, liposomes, and carbon-based nanomaterials for neuroprotection in the acute phase. We also review the design and neural regenerative application of electrospun scaffolds, conduits, and self-assembling peptide scaffolds.

Graphical abstract: Nanomedicine for treating spinal cord injury

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Publication details

The article was received on 24 Feb 2013, accepted on 09 Jul 2013 and first published on 16 Jul 2013


Article type: Review Article
DOI: 10.1039/C3NR00957B
Citation: Nanoscale, 2013,5, 8821-8836

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    Nanomedicine for treating spinal cord injury

    J. Y. Tyler, X. Xu and J. Cheng, Nanoscale, 2013, 5, 8821
    DOI: 10.1039/C3NR00957B

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