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Issue 3, 2010
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Nanoneedle: A multifunctional tool for biological studies in living cells

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Abstract

Studying biology in living cells is methodologically challenging but highly beneficial. Recent advances in nanobiotechnology offer exciting new opportunities to address this challenge. The nanoneedle technology, as an emerging technology that uses a cell membrane-penetrating nanoneedle to probe and manipulate biological processes in living cells, is expected to play an important role in this endeavor. Here we review the recent development and future direction of the nanoneedle technology for biological studies in living cells. The nanoneedle technology is shown to be powerful and versatile, and can offer numerous new ways to explore biological processes and biophysical properties of living cells with high spatial and temporal precision potentially reaching molecular resolution.

Graphical abstract: Nanoneedle: A multifunctional tool for biological studies in living cells

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Publication details

The article was received on 21 Aug 2009, accepted on 26 Oct 2009 and first published on 09 Dec 2009


Article type: Feature Article
DOI: 10.1039/B9NR00231F
Citation: Nanoscale, 2010,2, 363-372

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    Nanoneedle: A multifunctional tool for biological studies in living cells

    K. Yum, N. Wang and M. Yu, Nanoscale, 2010, 2, 363
    DOI: 10.1039/B9NR00231F

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