Jump to main content
Jump to site search
PLANNED MAINTENANCE Close the message box

Scheduled maintenance work on Wednesday 27th March 2019 from 11:00 AM to 1:00 PM (GMT).

During this time our website performance may be temporarily affected. We apologise for any inconvenience this might cause and thank you for your patience.


Issue 2, 2019
Previous Article Next Article

2-Formylpyrrole natural products: origin, structural diversity, bioactivity and synthesis

Author affiliations

Abstract

Covering: up to April 2018

2-Formylpyrroles are ubiquitous in nature, arising from the non-enzymatic Maillard reactions of amines and sugars. Often confused for secondary metabolites, these Maillard products display interesting biological activities including hepatoprotective, immunostimulatory, antiproliferative and antioxidant effects. This review presents all 2-formylpyrrole natural products reported to date and identifies structural sub-classes for their categorisation. The origin, biological activity and chemical syntheses of these natural products are discussed herein.

Graphical abstract: 2-Formylpyrrole natural products: origin, structural diversity, bioactivity and synthesis

Back to tab navigation

Publication details

The article was received on 13 Jun 2018 and first published on 24 Jul 2018


Article type: Review Article
DOI: 10.1039/C8NP00051D
Citation: Nat. Prod. Rep., 2019,36, 289-306

  •   Request permissions

    2-Formylpyrrole natural products: origin, structural diversity, bioactivity and synthesis

    James M. Wood, D. P. Furkert and M. A. Brimble, Nat. Prod. Rep., 2019, 36, 289
    DOI: 10.1039/C8NP00051D

Search articles by author

Spotlight

Advertisements