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Issue 1, 2016
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TCM, brain function and drug space

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Abstract

Covering: up to 2015

Traditional Chinese medicine has played a significant role in the mainstream healthcare system in China for thousands of years. Here, we summarize 84 major compounds from 15 selected herbal medicines targeting neurodegenerative diseases. We present a perspective based on the analysis of physicochemical properties of these TCM compounds, and comparison with current drugs and candidates for the treatment of Parkinson's and Alzheimer's disease. The results demonstrate that traditional Chinese medicines contain compounds possessing physicochemical properties that have excellent overlap with developed western medicines.

Graphical abstract: TCM, brain function and drug space

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Publication details

The article was received on 01 May 2015 and first published on 19 Nov 2015


Article type: Review Article
DOI: 10.1039/C5NP00049A
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Citation: Nat. Prod. Rep., 2016,33, 6-25

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    TCM, brain function and drug space

    C. Tang, Y. Ye, Y. Feng and R. J. Quinn, Nat. Prod. Rep., 2016, 33, 6
    DOI: 10.1039/C5NP00049A

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