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Issue 12, 2010
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Structure, bioactivities, biosynthetic relationships and chemical synthesis of the spirodioxynaphthalenes

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Abstract

Covering: 1989 to September 2010

The spirodioxynaphthalenes are a group of fungal secondary metabolites, consisting of a 1,8-dihydroxynaphthalene-derived spiroketal unit linked to a second oxidized naphthalene moiety, that show a great variety of biological activities. This review summarizes the research on the isolation, structure elucidation, biological activities, biosynthesis, and chemical synthesis of the spirodioxynaphthalenes published over the last 20 years. More than 100 fungal and plant metabolites are described, and over 100 references cited.

Graphical abstract: Structure, bioactivities, biosynthetic relationships and chemical synthesis of the spirodioxynaphthalenes

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Publication details

The article was received on 29 Aug 2010 and first published on 01 Nov 2010


Article type: Review Article
DOI: 10.1039/C0NP00031K
Nat. Prod. Rep., 2010,27, 1840-1870

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    Structure, bioactivities, biosynthetic relationships and chemical synthesis of the spirodioxynaphthalenes

    Y. Cai, Y. Guo and K. Krohn, Nat. Prod. Rep., 2010, 27, 1840
    DOI: 10.1039/C0NP00031K

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