Biological activities of pyridoacridines

Abstract

Covering: 1983–2003

This review consolidates biological activity data reported for pyridoacridine 1 molecules in the literature from 1983–2003 into several tables with brief discussions of assays used and results obtained. This review summarizes recent progress in structure activity relationships for analogues of amphimedine 2 and ascididemin 3 classes of pyridoacridines and correlates reported molecular mechanisms of action with biological activities.