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Issue 20, 2018
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New insights for the preparation of cytidine containing nucleotides using a soluble ether-linked polyethylene glycol support

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Abstract

We proposed an improved methodology for soluble PEG-supported synthesis of 5′-nucleotide derivatives from cytidine using a carboxylethoxy linker. Compared to our previous work, no by-product is formed during cleavage from the support and dialysis is not required anymore for purification.

Graphical abstract: New insights for the preparation of cytidine containing nucleotides using a soluble ether-linked polyethylene glycol support

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Supplementary files

Article information


Submitted
27 Jul 2018
Accepted
10 Sep 2018
First published
10 Sep 2018

New J. Chem., 2018,42, 16441-16445
Article type
Letter

New insights for the preparation of cytidine containing nucleotides using a soluble ether-linked polyethylene glycol support

A. Depaix, J. Puy, B. Roy and S. Peyrottes, New J. Chem., 2018, 42, 16441
DOI: 10.1039/C8NJ03753A

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