Jump to main content
Jump to site search
PLANNED MAINTENANCE Close the message box

Scheduled maintenance work on Wednesday 27th March 2019 from 11:00 AM to 1:00 PM (GMT).

During this time our website performance may be temporarily affected. We apologise for any inconvenience this might cause and thank you for your patience.


Issue 18, 2018
Previous Article Next Article

Acylhydrazone as a novel “Off–On–Off” fluorescence probe for the sequential detection of Al3+ and F

Author affiliations

Abstract

A new acylhydrazone fluorescence probe, SPBH, was synthesized from salicylaldehyde and 4-(pyridin-4-yl)benzohydrazide (PBH). SPBH exhibited high selectivity and a sensitive fluorescence response towards Al3+, even in the presence of other competing metal ions in DMF/H2O (1 : 1, v/v) medium. And, the chemosensor can even detect Al3+ in the intracellular region of human non-small cell lung cancer H460 cells. The binding phenomenon of SPBH was investigated by 1H NMR spectroscopy and HR-MS. Mass spectrometry analysis showed a 1 : 1 complex formation of SPBH with Al3+. The Job plot also confirmed its 1 : 1 interaction. This SPBH/Al3+ complex exhibited excellent fluorescence “turn-off” properties towards the F anion. Thus, SPBH acts as a sequential fluorescence “Off–On–Off” probe. The limits of detection for Al3+ and F were calculated from the titration curve and found to be 1.1 × 10−7 M and 1.47 × 10−6 M, respectively.

Graphical abstract: Acylhydrazone as a novel “Off–On–Off” fluorescence probe for the sequential detection of Al3+ and F−

Back to tab navigation

Supplementary files

Publication details

The article was received on 18 May 2018, accepted on 27 Jul 2018 and first published on 30 Jul 2018


Article type: Paper
DOI: 10.1039/C8NJ02474J
Citation: New J. Chem., 2018,42, 14978-14985

  •   Request permissions

    Acylhydrazone as a novel “Off–On–Off” fluorescence probe for the sequential detection of Al3+ and F

    Y. Wu, F. Rahman, M. Z. Bhatti, S. Yu, B. Yang, H. Wang, Z. Li and D. Zhang, New J. Chem., 2018, 42, 14978
    DOI: 10.1039/C8NJ02474J

Search articles by author

Spotlight

Advertisements