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Issue 18, 2018
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A fluorometric and colorimetric dual-mode sensor based on nitrogen and iron co-doped graphene quantum dots for detection of ferric ions in biological fluids and cellular imaging

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Abstract

N, Fe co-doped graphene quantum dots (N, Fe-GQDs) with excellent fluorescence performance were prepared by a simple one-pot hydrothermal method. During this process a dual doping strategy with chelated metal ions in combination with nitrogen passivation was developed. With this strategy, introducing Fe and retaining more oxygen-containing groups by chelation, in conjunction with N passivation, led to a dramatic enhancement of photoluminescence for N, Fe-GQDs. Furthermore, a fluorometric and colorimetric dual mode nanosensor based on the N, Fe-GQDs was prepared for effective and selective detecting of Fe3+ ions. More significantly, it was found that the as-prepared N, Fe-GQDs can be applied to detection of Fe3+ ions in biological samples and cellular imaging, which has a huge potential for utilization in practical applications.

Graphical abstract: A fluorometric and colorimetric dual-mode sensor based on nitrogen and iron co-doped graphene quantum dots for detection of ferric ions in biological fluids and cellular imaging

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Supplementary files

Article information


Submitted
14 Apr 2018
Accepted
12 Jul 2018
First published
17 Jul 2018

New J. Chem., 2018,42, 14751-14756
Article type
Paper

A fluorometric and colorimetric dual-mode sensor based on nitrogen and iron co-doped graphene quantum dots for detection of ferric ions in biological fluids and cellular imaging

X. X. Gao, X. Zhou, Y. F. Ma, C. P. Wang and F. X. Chu, New J. Chem., 2018, 42, 14751 DOI: 10.1039/C8NJ01805G

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