Development of a mitochondrial-targeted two-photon fluorescence turn-on probe for formaldehyde and its bio-imaging applications in living cells and tissues

An Xu; Yonghe Tang; Weiying Lin

doi:10.1039/C8NJ01240G

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Development of a mitochondrial-targeted two-photon fluorescence turn-on probe for formaldehyde and its bio-imaging applications in living cells and tissues†

An Xu,^a Yonghe Tang

^a and Weiying Lin

*^a

Author affiliations

* Corresponding authors

^a Institute of Fluorescent Probes for Biological Imaging, School of Chemistry and Chemical Engineering, School of Materials Science and Engineering, University of Jinan, Jinan, Shandong 250022, P. R. China
E-mail: weiyinglin2013@163.com

Abstract

A mitochondrial-targeted two-photon fluorescent formaldehyde probe (MT-FA) with a large emission enhancement was developed. MT-FA could image formaldehyde in the mitochondria of living cells for the first time, and also could image formaldehyde in living liver tissue slices.

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Article information

DOI: https://doi.org/10.1039/C8NJ01240G
Article type: Letter
Submitted: 13 Mar 2018
Accepted: 13 Apr 2018
First published: 16 Apr 2018

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New J. Chem., 2018,42, 8325-8329

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Development of a mitochondrial-targeted two-photon fluorescence turn-on probe for formaldehyde and its bio-imaging applications in living cells and tissues

A. Xu, Y. Tang and W. Lin, New J. Chem., 2018, 42, 8325 DOI: 10.1039/C8NJ01240G

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New Journal of Chemistry

Development of a mitochondrial-targeted two-photon fluorescence turn-on probe for formaldehyde and its bio-imaging applications in living cells and tissues†

Abstract

Supplementary files

Article information

Download Citation

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Development of a mitochondrial-targeted two-photon fluorescence turn-on probe for formaldehyde and its bio-imaging applications in living cells and tissues

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