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Issue 9, 2016
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A dual-site two-photon fluorescent probe for visualizing mitochondrial aminothiols in living cells and mouse liver tissues

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Abstract

Thiol-containing amino acids (RSH) play a key role in maintaining the redox environment. In this work, we developed a novel dual-site two-photon (TP) fluorescent RSH probe (CA-TPP) for imaging mitochondrial RSH in living cells and mouse liver tissues. This probe exhibited rapid response and high TP photostability towards mitochondrial RSH. In particular, probe CA-TPP was capable of using TP fluorescence to track mitochondrial RSH over a long period.

Graphical abstract: A dual-site two-photon fluorescent probe for visualizing mitochondrial aminothiols in living cells and mouse liver tissues

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Publication details

The article was received on 31 Jan 2016, accepted on 15 Jun 2016 and first published on 17 Jun 2016


Article type: Paper
DOI: 10.1039/C6NJ00330C
New J. Chem., 2016,40, 7399-7406

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    A dual-site two-photon fluorescent probe for visualizing mitochondrial aminothiols in living cells and mouse liver tissues

    F. Meng, Y. Liu, X. Yu and W. Lin, New J. Chem., 2016, 40, 7399
    DOI: 10.1039/C6NJ00330C

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