Issue 9, 2015

A protein–polymer hybrid gene carrier based on thermophilic histone and polyethylenimine

Abstract

A protein–polymer hybrid gene carrier HEP was successfully constructed based on thermophilic histone and polyethylenimine. The carrier exhibited low cytotoxicity and a high transfection efficiency due to the synergistic effects between the two components, which makes it a potential vehicle in tumor gene therapy.

Graphical abstract: A protein–polymer hybrid gene carrier based on thermophilic histone and polyethylenimine

Supplementary files

Article information

Article type
Letter
Submitted
20 May 2015
Accepted
28 Jun 2015
First published
29 Jun 2015

New J. Chem., 2015,39, 6718-6721

A protein–polymer hybrid gene carrier based on thermophilic histone and polyethylenimine

H. Shi, H. Han, Z. Xing, J. Chen, Y. Wang, A. Zhang, W. Shi and Q. Li, New J. Chem., 2015, 39, 6718 DOI: 10.1039/C5NJ01272D

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