Pd(OAc)2 and (DHQD)2PHAL as a simple, efficient and recyclable/reusable catalyst system for Suzuki–Miyaura cross-coupling reactions in H2O at room temperature

Abstract

Suzuki–Miyaura cross-coupling reaction catalyzed by Pd(OAc)₂–(DHQD)₂PHAL is a very simple, mild and efficient protocol for the synthesis of biaryls/heterobiaryls in neat H₂O at room temperature. The catalyst system is recyclable/reusable and can be employed in several consecutive runs without significant loss in catalytic activity.