Issue 12, 2010

Calixarenes: from biomimetic receptors to multivalent ligands for biomolecular recognition

Abstract

Calixarenes are versatile platforms for the design and synthesis of molecular receptors and multivalent ligands that are able to mimic or affect specific biological functions. This review illustrates examples spanning the recognition of small peptides and carbohydrates to ion transport through membranes, biomimetic catalysis, DNA condensation and cell transfection, protein binding, sensing and inhibition, and gives perspectives for using calixarene macrocycles in bio-supramolecular chemistry.

Graphical abstract: Calixarenes: from biomimetic receptors to multivalent ligands for biomolecular recognition

Article information

Article type
Perspective
Submitted
16 Apr 2010
Accepted
20 Jul 2010
First published
20 Sep 2010

New J. Chem., 2010,34, 2715-2728

Calixarenes: from biomimetic receptors to multivalent ligands for biomolecular recognition

F. Sansone, L. Baldini, A. Casnati and R. Ungaro, New J. Chem., 2010, 34, 2715 DOI: 10.1039/C0NJ00285B

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