A bioinspired hybrid silica–protein material with antimicrobial activity by iron uptake

Fernando Carmona; Daniela Mendoza; Alicia Megía-Fernández; Francisco Santoyo-Gonzalez; José M. Domínguez-Vera

doi:10.1039/C3MT20211A

Jump to main content

Jump to site search

SCHEDULED MAINTENANCE

Maintenance work is planned for Wednesday 1st May 2024 from 9:00am to 11:00am (BST).

During this time, the performance of our website may be affected - searches may run slowly and some pages may be temporarily unavailable. If this happens, please try refreshing your web browser or try waiting two to three minutes before trying again.

We apologise for any inconvenience this might cause and thank you for your patience.

You do not have JavaScript enabled. Please enable JavaScript to access the full features of the site or access our non-JavaScript page.

A bioinspired hybrid silica–protein material with antimicrobial activity by iron uptake†

Fernando Carmona,^ab Daniela Mendoza,^a Alicia Megía-Fernández,^bc Francisco Santoyo-Gonzalez^bc and José M. Domínguez-Vera*^ab

Author affiliations

* Corresponding authors

^a Departamento de Química Inorgánica, Facultad de Ciencias, Universidad de Granada, 18071 Granada, Spain
E-mail: josema@ugr.es
Fax: +34 958 428526
Tel: +34 958248097

^b Instituto de Biotecnología. Universidad de Granada, Spain

^c Departamento de Química Orgánica, Facultad de Ciencias. Universidad de Granada, 18071 Granada, Spain

Abstract

A silica–protein hybrid material has been prepared by simultaneous covalent deposition of apoferritin and lactoferrin on functionalized silica. This material exhibits strong antibacterial activity against E. coli due to its high iron-uptake capacity.