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Issue 11, 2010
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Zinc release of Zn7-metallothionein-3 induces fibrillar type amyloid-β aggregates

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Abstract

The reactive oxygen species H2O2 promotes the Zn7-metallothionein-3 induced 40 aggregation of fibrillar type structures via slow cysteine oxidation and Zn2+ release, whereas amorphous aggregates are formed by addition of Zn2+ to 40.

Graphical abstract: Zinc release of Zn7-metallothionein-3 induces fibrillar type amyloid-β aggregates

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Supplementary files

Article information


Submitted
02 Jul 2010
Accepted
04 Oct 2010
First published
21 Oct 2010

Metallomics, 2010,2, 741-744
Article type
Communication

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