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Issue 1, 2010
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Bioinformatics in bioinorganic chemistry

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Bioinformatics is a central discipline in modern life sciences aimed at describing the complex properties of living organisms starting from large-scale data sets of cellular constituents such as genes and proteins. In order for this wealth of information to provide useful biological knowledge, databases and software tools for data collection, analysis and interpretation need to be developed. In this paper, we review recent advances in the design and implementation of bioinformatics resources devoted to the study of metals in biological systems, a research field traditionally at the heart of bioinorganic chemistry. We show how metalloproteomes can be extracted from genome sequences, how structural properties can be related to function, how databases can be implemented, and how hints on interactions can be obtained from bioinformatics.

Graphical abstract: Bioinformatics in bioinorganic chemistry

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The article was received on 22 Jun 2009, accepted on 08 Sep 2009 and first published on 29 Sep 2009

Article type: Tutorial Review
DOI: 10.1039/B912156K
Metallomics, 2010,2, 39-51

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    Bioinformatics in bioinorganic chemistry

    I. Bertini and G. Cavallaro, Metallomics, 2010, 2, 39
    DOI: 10.1039/B912156K

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