The preparation of Au NP complexes of the premiRNA-145/GFP expressing plasmid is reported; the latter is successfully delivered to glioma cells and the transcripted miRNA-145 efficiently decreases the expression of its target gene, connective tissue growth factor (CTGF).
E. Benisvy-Aharonovich, U. Shimanovich, N. Kronfeld, N. Giladi, A. Bier, G. Kazimirsky, A. Gedanken and C. Brodie, Med. Chem. Commun., 2014, 5, 459 DOI: 10.1039/C3MD00314K
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