Issue 7, 2010
From the journal:

Molecular BioSystems

Direct evaluation of cellular internalization rates using chromogenic disulfides†‡

Megan E. Bucksa  and  Sergey N. Savinov*a  

* Corresponding authors

a Department of Chemistry, Purdue University, West Lafayette, USA
E-mail: ssavinov@purdue.edu
Fax: +1-765-494-0239
Tel: +1-765-494-5258

Abstract

A practical assay, which exploits the maintenance of the cytoplasmic redox balance in live cells, has been developed to report in real time on relative cellular internalization rates of molecules derivatized as chromogenic disulfides.

Graphical abstract: Direct evaluation of cellular internalization rates using chromogenic disulfides

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Article information

DOI
https://doi.org/10.1039/C003969A
Article type
Communication
Submitted
09 Mar 2010
Accepted
07 Apr 2010
First published
20 Apr 2010

Mol. BioSyst., 2010,6, 1176-1179

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Direct evaluation of cellular internalization rates using chromogenic disulfides

M. E. Bucks and S. N. Savinov, Mol. BioSyst., 2010, 6, 1176 DOI: 10.1039/C003969A

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