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Issue 4, 2007
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Artificial protein sensors

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Abstract

Protein recognition by synthetic molecules is a challenging endeavour, since these materials must bind to a large relatively flat surface domain and recognize a unique distribution of amino acid residues of varying charge, size and shape. The most promising routes involve specific metal coordination, epitope-docking on miniature proteins, aptamer selection, nonnatural peptide isosteres, functionalized platforms, secondary structure mimetics, molecular imprinting and receptors embedded in lipid layers.

Graphical abstract: Artificial protein sensors

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Publication details

The article was received on 28 Sep 2006, accepted on 22 Nov 2006 and first published on 08 Jan 2007


Article type: Highlight
DOI: 10.1039/B614103J
Mol. BioSyst., 2007,3, 241-248

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    Artificial protein sensors

    T. Schrader and S. Koch, Mol. BioSyst., 2007, 3, 241
    DOI: 10.1039/B614103J

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