Jump to main content
Jump to site search

Issue 3, 2020
Previous Article Next Article

Frequency dependent multiphase flows on centrifugal microfluidics

Author affiliations

Abstract

The simultaneous flow of gas and liquids in large scale conduits is an established approach to enhance the performance of different working systems under critical conditions. On the microscale, the use of gas–liquid flows is challenging due to the dominance of surface tension forces. Here, we present a technique to generate common gas–liquid flows on a centrifugal microfluidic platform. It consists of a spiral microchannel and specific micro features that allow for temporal and local control of stratified and slug flow regimes. We investigate several critical parameters that induce different gas–liquid flows and cause the transition between stratified and slug flows. We have analytically derived formulations that are compared with our experimental results to deliver a general guideline for designing specific gas–liquid flows. As an application of the gas–liquid flows in enhancing microfluidic systems' performance, we show the acceleration of the cell growth of E. coli bacteria in comparison to traditional culturing methods.

Graphical abstract: Frequency dependent multiphase flows on centrifugal microfluidics

Back to tab navigation

Supplementary files

Article information


Submitted
17 Sep 2019
Accepted
13 Dec 2019
First published
16 Dec 2019

This article is Open Access

Lab Chip, 2020,20, 514-524
Article type
Paper

Frequency dependent multiphase flows on centrifugal microfluidics

E. Pishbin, A. Kazemzadeh, M. Chimerad, S. Asiaei, M. Navidbakhsh and A. Russom, Lab Chip, 2020, 20, 514
DOI: 10.1039/C9LC00924H

This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence. Material from this article can be used in other publications provided that the correct acknowledgement is given with the reproduced material and it is not used for commercial purposes.

Reproduced material should be attributed as follows:

  • For reproduction of material from NJC:
    [Original citation] - Published by The Royal Society of Chemistry (RSC) on behalf of the Centre National de la Recherche Scientifique (CNRS) and the RSC.
  • For reproduction of material from PCCP:
    [Original citation] - Published by the PCCP Owner Societies.
  • For reproduction of material from PPS:
    [Original citation] - Published by The Royal Society of Chemistry (RSC) on behalf of the European Society for Photobiology, the European Photochemistry Association, and RSC.
  • For reproduction of material from all other RSC journals:
    [Original citation] - Published by The Royal Society of Chemistry.

Information about reproducing material from RSC articles with different licences is available on our Permission Requests page.


Social activity

Search articles by author

Spotlight

Advertisements