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Issue 20, 2016
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Screw-actuated displacement micropumps for thermoplastic microfluidics

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Abstract

The fabrication of on-chip displacement pumps integrated into thermoplastic chips is explored as a simple and low cost method for achieving precise and programmable flow control for disposable microfluidic systems. The displacement pumps consist of stainless steel screws inserted into threaded ports machined into a thermoplastic substrate which also serve as on-chip reagent storage reservoirs. Three different methods for pump sealing are investigated to enable high pressure flows without leakage, and software-defined control of multiple pumps is demonstrated in a self-contained platform using a compact and self-contained microcontroller for operation. Using this system, flow rates ranging from 0.5–40 μl min−1 are demonstrated. The pumps are combined with on-chip burst valves to fully seal multiple reagents into fabricated chips while providing on-demand fluid distribution in a downstream microfluidic network, and demonstrated for the generation of size-tunable water-in-oil emulsions.

Graphical abstract: Screw-actuated displacement micropumps for thermoplastic microfluidics

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Publication details

The article was received on 07 Jul 2016, accepted on 09 Sep 2016 and first published on 13 Sep 2016


Article type: Paper
DOI: 10.1039/C6LC00862C
Lab Chip, 2016,16, 3940-3946

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    Screw-actuated displacement micropumps for thermoplastic microfluidics

    J. Y. Han, O. D. Rahmanian, E. L. Kendall, N. Fleming and D. L. DeVoe, Lab Chip, 2016, 16, 3940
    DOI: 10.1039/C6LC00862C

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