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Issue 22, 2013
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Application of [18F]FDG in radiolabeling reactions using microfluidic technology

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Abstract

Radiolabeling of peptides with the short-lived positron emitter fluorine-18 is usually a challenging endeavour. Conventional radiolabeling reactions mostly require fairly large amounts of peptides as labeling precursors, and extensive synthesis times. Intrinsic advantages of microfluidic technology permit to overcome these hurdles. Herein, we describe how microfluidic technology combined with [18F]FDG as readily available PET radiotracer allows for fast and high yielding radiolabeling reactions of peptides with fluorine-18.

Graphical abstract: Application of [18F]FDG in radiolabeling reactions using microfluidic technology

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Publication details

The article was received on 03 Jul 2013, accepted on 20 Aug 2013 and first published on 20 Aug 2013


Article type: Communication
DOI: 10.1039/C3LC50797A
Lab Chip, 2013,13, 4290-4294

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    Application of [18F]FDG in radiolabeling reactions using microfluidic technology

    V. R. Bouvet and F. Wuest, Lab Chip, 2013, 13, 4290
    DOI: 10.1039/C3LC50797A

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