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Issue 10, 2013
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Optically clear alginate hydrogels for spatially controlled cell entrapment and culture at microfluidic electrode surfaces

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Abstract

We describe an innovation in the immobilization, culture, and imaging of cells in calcium alginate within microfluidic devices. This technique allows unprecedented optical access to the entirety of the calcium alginate hydrogel, enabling observation of growth and behavior in a chemical and mechanical environment favored by many kinds of cells.

Graphical abstract: Optically clear alginate hydrogels for spatially controlled cell entrapment and culture at microfluidic electrode surfaces

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Article information


Submitted
16 Jan 2013
Accepted
18 Mar 2013
First published
05 Apr 2013

Lab Chip, 2013,13, 1854-1858
Article type
Technical Innovation

Optically clear alginate hydrogels for spatially controlled cell entrapment and culture at microfluidic electrode surfaces

J. F. Betz, Y. Cheng, C. Tsao, A. Zargar, H. Wu, X. Luo, G. F. Payne, W. E. Bentley and G. W. Rubloff, Lab Chip, 2013, 13, 1854
DOI: 10.1039/C3LC50079A

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