Issue 6, 2013

Time-of-flight magnetic flow cytometry in whole blood with integrated sample preparation

Abstract

Rapid and specific rare cell detection for point-of-care testing requires an integration of the sample preparation for flow cytometry. To achieve such a challenging goal we have developed a magnetic flow cytometry technique which applies magnetophoresis to perform cell enrichment, focusing, and background elimination in a single step. Time-of-flight measurements are performed with integrated magnetic sensors to detect specifically cancer cells and cell diameters in whole blood.

Graphical abstract: Time-of-flight magnetic flow cytometry in whole blood with integrated sample preparation

Supplementary files

Article information

Article type
Technical Innovation
Submitted
27 Nov 2012
Accepted
17 Jan 2013
First published
18 Jan 2013

Lab Chip, 2013,13, 1035-1038

Time-of-flight magnetic flow cytometry in whole blood with integrated sample preparation

M. Helou, M. Reisbeck, S. F. Tedde, L. Richter, L. Bär, J. J. Bosch, R. H. Stauber, E. Quandt and O. Hayden, Lab Chip, 2013, 13, 1035 DOI: 10.1039/C3LC41310A

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