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Issue 4, 2013
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Control of sequential fluid delivery in a fully autonomous capillary microfluidic device

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Abstract

Microfluidics and miniaturization of biosensors are fundamental for the development of point-of-care (PoC) diagnostic and analytical tools with the potential of decreasing reagent consumption and time of analysis while increasing portability. However, interfacing microfluidics with fluid control systems is still a limiting factor in practical implementation. We demonstrate an innovative capillary microfluidic design that allows sequential insertion of controlled volumes of liquids into a microfluidic channel with general applicability. The system requires only the placing of liquids at the corresponding inlets. Subsequently, the different solutions flow inside the microfluidic device sequentially and autonomously without the use of valves using integrated capillary pumps. The capillary microfluidic system is demonstrated with a model immunoassay.

Graphical abstract: Control of sequential fluid delivery in a fully autonomous capillary microfluidic device

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Article information


Submitted
27 Jun 2012
Accepted
19 Nov 2012
First published
19 Nov 2012

Lab Chip, 2013,13, 641-645
Article type
Technical Innovation

Control of sequential fluid delivery in a fully autonomous capillary microfluidic device

P. Novo, F. Volpetti, V. Chu and J. P. Conde, Lab Chip, 2013, 13, 641
DOI: 10.1039/C2LC41083D

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