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Issue 23, 2012
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A simple packed bed device for antibody labelled rare cell capture from whole blood

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Abstract

We have developed a system to isolate rare cells from whole blood using commercially available components and simple microfluidics. We characterized the capture of MCF-7 cells spiked into whole human blood using this system to demonstrate that enrichment and enumeration studies give results similar to in situ surface-modified devices while reducing fabrication and operation complexity.

Graphical abstract: A simple packed bed device for antibody labelled rare cell capture from whole blood

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Article information


Submitted
07 Aug 2012
Accepted
24 Sep 2012
First published
26 Sep 2012

Lab Chip, 2012,12, 4972-4975
Article type
Technical Innovation

A simple packed bed device for antibody labelled rare cell capture from whole blood

J. G. Kralj, C. Arya, A. Tona, T. P. Forbes, M. S. Munson, L. Sorbara, S. Srivastava and S. P. Forry, Lab Chip, 2012, 12, 4972
DOI: 10.1039/C2LC41048F

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