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Issue 18, 2012
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Magnetically-actuated blood filter unit attachable to pre-made biochips

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Abstract

We present a novel blood filter unit that is designed to separate blood plasma from whole blood by simple magnetic actuation. A non-diluted blood sample is dropped into the filter unit and magnetic attraction is applied to squeeze out only blood plasma while blood particles are filtered by membranes stacked in the filter unit. The new filter device yields good filtering performance with nearly perfect filtering efficiency (∼99.999%), high plasma recovery (∼30%), low blood consumption (<50 μl), and fast operation (∼1 min). Because it is simple to operate and is attachable to any kind of pre-made biochip, it has commercial potential in various lab-on-a-chip applications for blood tests.

Graphical abstract: Magnetically-actuated blood filter unit attachable to pre-made biochips

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Article information


Submitted
08 May 2012
Accepted
26 Jun 2012
First published
26 Jun 2012

Lab Chip, 2012,12, 3272-3276
Article type
Technical Innovation

Magnetically-actuated blood filter unit attachable to pre-made biochips

K. H. Chung, Y. H. Choi, J. Yang, C. W. Park, W. Kim, C. S. Ah and G. Y. Sung, Lab Chip, 2012, 12, 3272
DOI: 10.1039/C2LC40529F

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