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Issue 7, 2011
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Integrated systems for rapid point of care (PoC) blood cell analysis

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Abstract

Counting the different subpopulations of cells in a fingerprick of human blood is important for a number of clinical point-of-care (PoC) applications. It is a challenge to demonstrate the integration of sample preparation and detection techniques in a single platform. In this paper we demonstrate a generic microfluidic platform that combines sample processing and characterisation and enumeration in a single, integrated system. Results of microfluidic 3-part differential leukocyte (granulocyte, lymphocyte and monocyte) counts, together with erythrocyte and thrombocyte (platelet) counts, in human blood are shown and corroborated with results from hospital clinical laboratory analysis.

Graphical abstract: Integrated systems for rapid point of care (PoC) blood cell analysis

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Article information


Submitted
11 Nov 2010
Accepted
20 Jan 2011
First published
17 Feb 2011

Lab Chip, 2011,11, 1249-1255
Article type
Paper

Integrated systems for rapid point of care (PoC) blood cell analysis

C. van Berkel, J. D. Gwyer, S. Deane, N. Green, J. Holloway, V. Hollis and H. Morgan, Lab Chip, 2011, 11, 1249
DOI: 10.1039/C0LC00587H

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