Issue 17, 2011
From the journal:

Lab on a Chip

A microchip-based model wound with multiple types of cells†

Yunyan Xie,ab   Wei Zhang,*a   Liming Wang,ab   Kang Sun,ab   Yi Sunab  and  Xingyu Jiang*a  

* Corresponding authors

a CAS Key Lab for Biological Effects of Nanomaterials and Nanosafety, National Center for NanoScience and Technology, 11 BeiYiTiao, ZhongGuanCun, Beijing, China
E-mail: xingyujiang@nanoctr.cn, zhangw@nanoctr.cn
Fax: +(86)6265 6765
Tel: +(86)8254 5558

b Graduate University of Chinese Academy of Sciences, ShiJingShan, YuQuan Road, 19 (A), Beijing, China

Abstract

Collective migration is critical to many physiological processes, but few methods allow for studying this behavior with precisely controlled cell–cell interaction. Here we report the development of a microchip based on co-culture of different types of cells and selective injury, and explore the dynamics of epithelial collective migration triggered by a real cell group.

Graphical abstract: A microchip-based model wound with multiple types of cells

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Supplementary files

Article information

DOI
https://doi.org/10.1039/C0LC00562B
Article type
Communication
Submitted
04 Nov 2010
Accepted
22 Jun 2011
First published
21 Jul 2011

Lab Chip, 2011,11, 2819-2822

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A microchip-based model wound with multiple types of cells

Y. Xie, W. Zhang, L. Wang, K. Sun, Y. Sun and X. Jiang, Lab Chip, 2011, 11, 2819 DOI: 10.1039/C0LC00562B

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