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Issue 4, 2011
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Hydrophobic modification of polycarbonate for reproducible and stable formation of biocompatible microparticles

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Abstract

We propose a simple and effective scheme for the modification of the walls of microfluidic channels fabricated in polycarbonate (PC) after the device has been bonded. The method prevents both static and dynamic wetting of PC by aqueous solutions including viscous, non-Newtonian solutions of polymers as e.g.alginate. The procedure uses dodecylamine, which readily reacts with the carbonate groups of PC to produce a hydrophobic surface. We characterize the dependence of the contact angles and homogeneity of the modified surfaces on the time, temperature, and concentration—all important parameters—of the reaction and provide optimal conditions for the process.

Graphical abstract: Hydrophobic modification of polycarbonate for reproducible and stable formation of biocompatible microparticles

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Article information


Submitted
31 Aug 2010
Accepted
10 Nov 2010
First published
06 Dec 2010

Lab Chip, 2011,11, 748-752
Article type
Technical Note

Hydrophobic modification of polycarbonate for reproducible and stable formation of biocompatible microparticles

P. Jankowski, D. Ogonczyk, A. Kosinski, W. Lisowski and P. Garstecki, Lab Chip, 2011, 11, 748
DOI: 10.1039/C0LC00360C

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