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Issue 20, 2010
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Fluidic microstructuring of alginate hydrogels for the single cell niche

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Abstract

Controlling alginate gel formation by diffusion of Ca2+ ions through a filter barrier, a layer-by-layer deposition technique with resolution on the size scale of a single cell is presented. It offers the possibility of exposing cells under biocompatible conditions to microheterogeneous three-dimensional environments, mimicking the layered structure of extracellular matrix in tissues.

Graphical abstract: Fluidic microstructuring of alginate hydrogels for the single cell niche

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Publication details

The article was received on 09 Apr 2010, accepted on 03 Aug 2010 and first published on 06 Sep 2010


Article type: Paper
DOI: 10.1039/C004988C
Lab Chip, 2010,10, 2771-2777

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    Fluidic microstructuring of alginate hydrogels for the single cell niche

    T. Braschler, A. Valero, L. Colella, K. Pataky, J. Brugger and P. Renaud, Lab Chip, 2010, 10, 2771
    DOI: 10.1039/C004988C

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