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Issue 14, 2009
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Spheroid array of fetal mouse liver cells constructed on a PEG-gel micropatterned surface: upregulation of hepatic functions by co-culture with nonparenchymal liver cells

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Abstract

A spheroid array of fetal mouse liver cells, which comprise various immature cells, was constructed on a PEG-gel micropatterned surface and its hepatic activity and degree of differentiation induction were significantly upregulated by co-culture with nonparenchymal liver cells as feeder-cells.

Graphical abstract: Spheroid array of fetal mouse liver cells constructed on a PEG-gel micropatterned surface: upregulation of hepatic functions by co-culture with nonparenchymal liver cells

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Article information


Submitted
17 Feb 2009
Accepted
18 May 2009
First published
28 May 2009

Lab Chip, 2009,9, 1991-1993
Article type
Communication

Spheroid array of fetal mouse liver cells constructed on a PEG-gel micropatterned surface: upregulation of hepatic functions by co-culture with nonparenchymal liver cells

R. Kojima, K. Yoshimoto, E. Takahashi, M. Ichino, H. Miyoshi and Y. Nagasaki, Lab Chip, 2009, 9, 1991
DOI: 10.1039/B903388B

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