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Issue 12, 2009
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High-radix microfluidic multiplexer with pressure valves of different thresholds

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Abstract

We propose high-radix microfluidic multiplexers that effectively address a large number of flow channels with a few control lines having pressure valves of different thresholds. Previous binary multiplexers address only two flow channels by controlling identical threshold pressure valves in two control lines; that is, they address 2n/2 flow channels by using n control lines. However, the proposed ternary or quaternary multiplexer (high-radix multiplexers) addresses three or four flow channels by controlling two or three kinds of pressure valves in two control lines, respectively. Thus, these multiplexers address 3n/2 and 4n/2 flow channels, which are results of increasing the radix from binary to quaternary. In experiments, we designed ternary (two kinds of valves) and quaternary (three kinds of valves) multiplexers and applied them to 3 × 3 and 4 × 4 well arrays with four control lines, respectively. We determine the static/dynamic operating conditions of the pressure valves having different thresholds in the ternary and quaternary multiplexers. Under these conditions, the ternary and quaternary multiplexers successfully address 3 × 3 and 4 × 4 well arrays by controlling two and three pressure valves of different thresholds in four control lines, respectively.

Graphical abstract: High-radix microfluidic multiplexer with pressure valves of different thresholds

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Publication details

The article was received on 19 Nov 2008, accepted on 02 Mar 2009 and first published on 30 Mar 2009


Article type: Paper
DOI: 10.1039/B820582E
Lab Chip, 2009,9, 1681-1686

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    High-radix microfluidic multiplexer with pressure valves of different thresholds

    D. W. Lee and Y. Cho, Lab Chip, 2009, 9, 1681
    DOI: 10.1039/B820582E

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