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Issue 10, 2008
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Microfluidic-based synthesis of non-spherical magnetic hydrogel microparticles

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Abstract

Spherical and non-spherical magnetic hydrogel particles were synthesized in a microfluidic device containing an embedded UV light reflector. Monodisperse magnetic emulsion droplets were generated in a T-junction and allowed to relax into spheres, disks, and plugs in confining microchannel geometries. Particle morphology was locked-in via UV-initiated photopolymerization. The role of the reflector in the microchannel is to provide a uniform distribution of UV energy to the magnetic emulsion droplets and to increase the UV flux, which significantly improves UV polymerization conditions for microfluidic-based particle synthesis. Magnetic nanoparticles were uniformly encapsulated in the hydrogel, giving the microparticles superparamagnetic behavior. Additionally, the non-spherical particles show anisotropic responses under an applied external magnetic field.

Graphical abstract: Microfluidic-based synthesis of non-spherical magnetic hydrogel microparticles

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Supplementary files

Article information


Submitted
27 Mar 2008
Accepted
03 Jun 2008
First published
06 Aug 2008

Lab Chip, 2008,8, 1640-1647
Article type
Paper

Microfluidic-based synthesis of non-spherical magnetic hydrogel microparticles

D. K. Hwang, D. Dendukuri and P. S. Doyle, Lab Chip, 2008, 8, 1640
DOI: 10.1039/B805176C

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