Integrated flow-cells for novel adjustable sheath flows

Abstract

In this paper two integrated flow-cells are presented that can generate novel sheath flows. The flow-cells allow for dynamic orthogonal control of the sample flow dimensions. In addition to this, the sample flow can be freely positioned inside the channel. The flow-cells are attractive, because they are very simple to fabricate and are compatible with the integration of sensors. Experiments have been carried out demonstrating that the sample flow dimensions can be controlled over a wide range; also the results show good agreement with finite element simulation results.