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Issue 17, 2012
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Electroactive and biocompatible hydroxyl- functionalized graphene by ball milling

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Abstract

Hydroxyl-functionalized graphene (G–OH) was efficiently produced from exfoliation of graphite powder by ball milling the presence of potassium hydroxide (KOH). While the nanoscale graphene sheets were confirmed by various characterization techniques, including atomic force microscopy (AFM), scanning electron microscopy (SEM), transmission electron microscopy (TEM), and UV-vis spectroscopy, the formation of hydroxyl groups in G–OH was revealed by Fourier transform infrared (FTIR), Nuclear Magnetic Resonance analysis (NMR), Raman and X-ray photoelectron spectroscopic (XPS) measurements. The as-prepared G–OH showed strong hydrophilicity with good solubility in water, excellent electrochemical activity and no influence on the growth of human retinal pigment epithelium (RPE) cells. More than 80% cell survival rate and less than 7% lactate dehydrogenase (LDH) release were observed for RPE cells treated with G–OH, indicating excellent biocompatibility.

Graphical abstract: Electroactive and biocompatible hydroxyl- functionalized graphene by ball milling

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Article information


Submitted
16 Feb 2012
Accepted
28 Feb 2012
First published
28 Feb 2012

J. Mater. Chem., 2012,22, 8367-8371
Article type
Paper

Electroactive and biocompatible hydroxyl- functionalized graphene by ball milling

L. Yan, M. Lin, C. Zeng, Z. Chen, S. Zhang, X. Zhao, A. Wu, Y. Wang, L. Dai, J. Qu, M. Guo and Y. Liu, J. Mater. Chem., 2012, 22, 8367
DOI: 10.1039/C2JM30961K

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