Issue 17, 2010
From the journal:

Journal of Materials Chemistry

Glucose-responsive polymer brushes for microcantilever sensing†‡

Tao Chen,a   Debby P. Chang,a   Ting Liu,b   Ramya Desikan,c   Ram Datar,d   Thomas Thundat,c   Rüdiger Bergerb  and  Stefan Zauscher*a  

* Corresponding authors

a Center for Biologically Inspired Materials and Materials Systems, and Department of Mechanical Engineering and Materials Science, Duke University, Durham, NC, USA
E-mail: zauscher@duke.edu

b Max Planck Institute for Polymer Research, Mainz, Germany

c Oak Ridge National Laboratory, Oak Ridge, TN, USA

d Biomedical Nanoscience Institute, University of Miami, Miami, FL, USA

Abstract

Glucose responsive polymer brushes were synthesized on gold substrates and microcantilever arrays. The response properties of these brushes were evaluated by exposing them to different glucose concentrations for a range of pH values. This work demonstrates the potential for polymer brush-functionalized micromechanical cantilevers as glucose detectors. Furthermore, the work demonstrates that stimulus-responsive polymer brushes on micromechanical cantilevers have a significantly larger bending response due to glucose binding compared with self-assembled monolayers.

Graphical abstract: Glucose-responsive polymer brushes for microcantilever sensing

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Article information

DOI
https://doi.org/10.1039/B925583D
Article type
Communication
Submitted
04 Dec 2009
Accepted
08 Feb 2010
First published
23 Feb 2010

J. Mater. Chem., 2010,20, 3391-3395

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Glucose-responsive polymer brushes for microcantilever sensing

T. Chen, D. P. Chang, T. Liu, R. Desikan, R. Datar, T. Thundat, R. Berger and S. Zauscher, J. Mater. Chem., 2010, 20, 3391 DOI: 10.1039/B925583D

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