Issue 46, 2008

Controlling the reactivity of calcium phosphate cements

Abstract

The effect of composition on the reactivity of a calcium phosphate cement (CPC) consisting of tricalcium phosphate (TCP)–water mixtures was investigated by isothermal calorimetry at 37 °C. The parameters of interest were the mean particle size of the powder, the use of small amounts of hydroxyapatite nanoparticles as nucleating agent, the phosphate concentration and the pH of the aqueous solution. Interactions of various parameters were also investigated. The results show that the main parameter controlling CPC reactivity was TCP particle size, because in contrast to other parameters it markedly reduced the total reaction time.

Graphical abstract: Controlling the reactivity of calcium phosphate cements

Article information

Article type
Paper
Submitted
14 Jul 2008
Accepted
19 Sep 2008
First published
24 Oct 2008

J. Mater. Chem., 2008,18, 5669-5675

Controlling the reactivity of calcium phosphate cements

M. Bohner, T. J. Brunner and W. J. Stark, J. Mater. Chem., 2008, 18, 5669 DOI: 10.1039/B811953H

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