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Issue 7, 2008
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Layer-by-layer assembly of magnetic polypeptide nanotubes as a DNA carrier

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Abstract

Biodegradable and multifunctionalized nanotubes are of special interest since they can be applied to biological systems including bioseparation, biocatalysis and biomolecule delivery. In this paper, magnetic polypeptide nanotubes were fabricated through the layer-by-layer (LbL) assembly of poly-L-lysine hydrochloride (PLL), poly-L-glutamic acid (PGA) and magnetic nanoparticles within the inner pores of polycarbonate templates with subsequent removal of the templates. The wall thickness and inner diameter of as-prepared nanotubes can be tuned by changing the assembled layers, and the length and outer diameter are dependent on the used templates. These magnetic polypeptide nanotubes can be used as a DNA carrier and manipulated under magnetic force.

Graphical abstract: Layer-by-layer assembly of magnetic polypeptide nanotubes as a DNA carrier

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Publication details

The article was received on 12 Oct 2007, accepted on 28 Nov 2007 and first published on 11 Jan 2008


Article type: Paper
DOI: 10.1039/B715770C
Citation: J. Mater. Chem., 2008,18, 748-754

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    Layer-by-layer assembly of magnetic polypeptide nanotubes as a DNA carrier

    Q. He, Y. Tian, Y. Cui, H. Möhwald and J. Li, J. Mater. Chem., 2008, 18, 748
    DOI: 10.1039/B715770C

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