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Issue 38, 2007
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Encapsulated photosensitive drugs by biodegradable microcapsules to incapacitate cancer cells

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Abstract

A hydrophobic photodynamic therapy drug, hypocrellin B (HB), was accumulated in water-solubilized natural polyelectrolyte microcapsules. The HB can be effectively encapsulated, delivered and subsequently taken up by cancer cells. These intracellular HB-loaded microcapsules show biocompatibility under darkness and high cytotoxicity after irradiation which provides the possibility of controlled delivery and release of drugs.

Graphical abstract: Encapsulated photosensitive drugs by biodegradable microcapsules to incapacitate cancer cells

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Article information


Submitted
05 Jun 2007
Accepted
10 Jul 2007
First published
27 Jul 2007

J. Mater. Chem., 2007,17, 4018-4021
Article type
Paper

Encapsulated photosensitive drugs by biodegradable microcapsules to incapacitate cancer cells

K. Wang, Q. He, X. Yan, Y. Cui, W. Qi, L. Duan and J. Li, J. Mater. Chem., 2007, 17, 4018
DOI: 10.1039/B708477C

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